mailing list manager

I'm looking for some software to manage email mailing lists for my business, so that I can keep in touch with groups of individuals (e.g., all my beta testers or previous customers, etc).

Ideally, it would have a web interface where I can add individuals to different lists, and users can remove themselves from any list they no longer wish to receive.

Anyone have any experience with any software that might fit the bill?

Edit: It'd be particularly awesome if I could track my users in a spreadsheet or SQL database and have the mailing list software be able to pull lists based on whether certain fields were set.


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